Excess Urinary Iodine Is Associated with Autoimmune Subclinical Hypothyroidism among Egyptian Women

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著者

    • GAD ADELA M.
    • Internal Medicine Depart. Faculty of Medicine for Girls, Al-Azhar University
    • ABDEL-BASET HODA
    • Internal Medicine Depart. Faculty of Medicine for Girls, Al-Azhar University
    • AZAB ADEL
    • Clinical Pathology Depart., Ain Shams University

抄録

Excessive iodine exposure was reported to be associated with thyroid dysfunctions.The aim of this study is to evaluate the link between excess urinary iodine as the prime indicator of excessive iodine intake and autoimmune subclinical hypothyroidism (SCH) among Egyptian women. Seventy three women with autoimmune SCH and 60 age- matched healthy women as controls were enrolled in this study. TSH, FT4, urinary iodine concentrations (UIC) and thyroid peroxidase antibody (TPOAb) were estimated. The levels of urinary iodine were significantly higher in patients with SCH as compared with control subjects, (326.97 112.98 <i>vs</i>. 274.45 98.75 ug/l, p<0.01). In patients with SCH, there was a significant correlation between UIC and TSH levels. Also, a significant correlation between UIC and TPOAb was found. We conclude that excessive iodine intake may trigger thyroid autoimmunity and eventually thyroid hypofunction among Egyptian women.<br>

収録刊行物

  • Endocrine journal  

    Endocrine journal 55(3), 601-605, 2008-06-01 

    The Japan Endocrine Society

参考文献:  26件

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各種コード

  • NII論文ID(NAID)
    10021266726
  • NII書誌ID(NCID)
    AA10901436
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    09188959
  • データ提供元
    CJP書誌  J-STAGE 
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