Epstein-Barr Virus (EBV) 関連胃癌手術7年後に発生したEBV関連残胃癌の1例 A case of epstein-barr virus (EBV) associated remnant gastric carcinoma arising 7 years after distal gastrectomy for EBV associated gastric carcinoma

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著者

    • 高橋 公一 TAKAHASHI Koichi
    • 埼玉医科大学消化器・一般外科 Department of Gastrointestinal Surgery, Saitama Medical University School of Medicine
    • 大谷 吉秀 OTANI Yoshihide
    • 埼玉医科大学消化器・肝臓内科 Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
    • 小川 展二 OGAWA Nobuji
    • 埼玉医科大学消化器・肝臓内科 Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
    • 安本 明浩 YASUMOTO Akihiro
    • 埼玉医科大学消化器・肝臓内科 Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
    • 竹田 明彦 TAKEDA Akihiko
    • 埼玉医科大学消化器・肝臓内科 Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
    • 宮澤 光男 MIYAZAWA Mitsuo
    • 埼玉医科大学消化器・肝臓内科 Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
    • 篠塚 望 SHINOZUKA Nozomi
    • 埼玉医科大学消化器・肝臓内科 Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
    • 小山 勇 KOYAMA Isamu
    • 埼玉医科大学消化器・肝臓内科 Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
    • 新井 晋 ARAI Shin
    • 埼玉医科大学消化器・肝臓内科 Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine

抄録

症例は52歳男性.平成10年7月胃前庭部に早期胃癌を認め,幽門側胃切除術を施行した.以後外来通院していたが,平成17年1月上部消化管内視鏡にて,食道胃接合部直下に0-IIa型早期癌を認めた.内視鏡的粘膜下層剥離術(ESD)を施行したが,組織所見で癌の浸潤が粘膜下組織内で粘膜筋板から0.5mm以深のsm2に広範囲に認められたため,残胃全摘術を施行した.どちらの病変も<i>EBV</i>陽性であった.<i>EBV</i>関連胃癌手術7年後の残胃に<i>EBV</i>関連胃癌が発生した症例を経験したので,文献的考察を加えて報告する.<br>

A 52-year-old man undergoing distal gastrectomy for gastric cancer in July 1998 was found to have a 0-IIa type gastric tumor near EC junction in January 2005. Histological examination showed the tumor was moderately differentiated adenocarcinoma. As the tumor was diagnosed as mucosal cancer, endoscopic mucosal dissection was performed. But pathological findings showed the depth of cancer cell invasion into deep submucosal layer. Then total resection of remnant stomach was performed. Both tumors were diagnosed as <i>EBV</i>-associated carcinoma. It is speculated that the mucosa changing after initial operation would give risk to a new occurrence of <i>EBV</i>-associated remnant gastric carcinoma. And then follow up after operation is important. Although some cases of <i>EBV</i>-associated remnant gastric carcinoma is found for short period after the primary surgery, our case second primary cancer was found 7 year after primary surgery. Long term follow-up by Endoscopy seems to be important.<br>

収録刊行物

  • 日本消化器病學會雜誌 = The Japanese journal of gastro-enterology  

    日本消化器病學會雜誌 = The Japanese journal of gastro-enterology 104(12), 1728-1732, 2007-12-05 

    The Japanese Society of Gastroenterology

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各種コード

  • NII論文ID(NAID)
    10021269774
  • NII書誌ID(NCID)
    AN00192124
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    04466586
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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