A case of <i>epstein-barr virus</i> (<i>EBV</i>) associated remnant gastric carcinoma arising 7 years after distal gastrectomy for <i>EBV</i> associated gastric carcinoma.

  • TAKAHASHI Koichi
    Department of Gastrointestinal Surgery, Saitama Medical University School of Medicine
  • OTANI Yoshihide
    Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
  • OGAWA Nobuji
    Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
  • YASUMOTO Akihiro
    Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
  • TAKEDA Akihiko
    Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
  • MIYAZAWA Mitsuo
    Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
  • SHINOZUKA Nozomi
    Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
  • KOYAMA Isamu
    Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
  • ARAI Shin
    Department of Gastroenterology and Hepatology, Saitama Medical University School of Medicine
  • OTA Shinichi
    Department of Pathology, Saitama Medical University School of Medicine
  • BAN Shinichi
    Department of Pathology, Saitama Medical University School of Medicine

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Other Title
  • <i>Epstein-Barr Virus</i>(<i>EBV</i>)関連胃癌手術7年後に発生した<i>EBV</i>関連残胃癌の1例

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Abstract

A 52-year-old man undergoing distal gastrectomy for gastric cancer in July 1998 was found to have a 0-IIa type gastric tumor near EC junction in January 2005. Histological examination showed the tumor was moderately differentiated adenocarcinoma. As the tumor was diagnosed as mucosal cancer, endoscopic mucosal dissection was performed. But pathological findings showed the depth of cancer cell invasion into deep submucosal layer. Then total resection of remnant stomach was performed. Both tumors were diagnosed as EBV-associated carcinoma. It is speculated that the mucosa changing after initial operation would give risk to a new occurrence of EBV-associated remnant gastric carcinoma. And then follow up after operation is important. Although some cases of EBV-associated remnant gastric carcinoma is found for short period after the primary surgery, our case second primary cancer was found 7 year after primary surgery. Long term follow-up by Endoscopy seems to be important.<br>

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