非定型抗酸菌症の治療中にみられた食道メラノーシスの1症例

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タイトル別名
  • ESOPHAGEAL MELANOSIS DEVELOPING DURING TREATMENT OF ATYPICAL MYCOBACTERIAL DISEASE: A CASE REPORT

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A 75-year-old male visited our hospital for medical chek-up . He had been on Rifampicin and Levofloxacin for treatment of atypical mycobacterial disease for the past 4 years . The first endoscopic examination disclosed the mucosa of the esophagus to be black from the upper to lower thoracic esophagus. Endoscopic biopsy specimen pathologically showed that the mucosal epithelium harbored abundant melanin granules and melanophages in the lamina propria . The second endoscopic examination after 6 months off Rifampicin and Levoflaxin revealed the entire disappearance of the black mucosa of the esophagus. A rare case of esophageal melanosis developing during treatment of Rifampicin and Levofloxacin was reported.

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