Double-filtration plasmapheresis (DFPP) with prednisolone improved an HTLV-1 positive patient with Castleman's disease

DOI Web Site 23 References
  • Maesato Kyoko
    Department of Nephrology, and Kidney & Dialysis Center, Shonan Kamakura General Hospital
  • Oka Machiko
    Department of Nephrology, and Kidney & Dialysis Center, Shonan Kamakura General Hospital
  • Mano Tsutomu
    Department of Nephrology, and Kidney & Dialysis Center, Shonan Kamakura General Hospital
  • Ikee Ryota
    Department of Nephrology, and Kidney & Dialysis Center, Shonan Kamakura General Hospital
  • Moriya Hidekazu
    Department of Nephrology, and Kidney & Dialysis Center, Shonan Kamakura General Hospital
  • Ohtake Takayasu
    Department of Nephrology, and Kidney & Dialysis Center, Shonan Kamakura General Hospital
  • Kobayashi Shuzo
    Department of Nephrology, and Kidney & Dialysis Center, Shonan Kamakura General Hospital

Bibliographic Information

Other Title
  • Ｄｏｕｂｌｅ‐ｆｉｌｔｒａｔｉｏｎ　ｐｌａｓｍａｐｈｅｒｅｓｉｓ（ＤＦＰＰ）とステロイド内服によりＨＤを離脱しえたＨＴＬＶ‐１抗体陽性全身型Ｃａｓｔｌｅｍａｎ病の１例
  • 症例報告 Double-filtration plasmapheresis(DFPP)とステロイド内服によりHDを離脱しえたHTLV-1抗体陽性全身型Castleman病の1例
  • ショウレイ ホウコク Double filtration plasmapheresis DFPP ト ステロイド ナイフク ニ ヨリ HD オ リダツシエタ HTLV 1 コウタイ ヨウセイ ゼンシンガタ Castlemanビョウ ノ 1レイ

Search this article

Abstract

We present a 50-year-old female patient with multicentric Castleman's disease. Since the patient had chronic renal failure of unknown etiology, hemodialysis therapy had been performed twice a week for eight months until she was admitted to our hospital. She had shown mild fever, lymph node swelling, and general fatigue for two years, and biochemical tests showed high levels of CRP, IL-6, HTLV-1 antibody, and polyclonal hypergammaglobulinemia. Lymph node biopsy showed idiopathic plasmacytic lymphoadenopathy, and renal biopsy demonstrated tubulointerstitial nephritis. Based on these data, we diagnosed the patient as having multicentric Castleman's disease along with renal dysfunction associated with Castleman's disease. DFPP (double-filtration plasmapheresis) and prednisolone therapy were started. After those therapies, renal function improved and hemodialysis therapy was finally discontinued. We should reevaluate hemodialysis patients with renal failure due to unknown etiology.

Journal

References(23)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top