Type 2 Diabetes Mellitus Requiring Large-dose Insulin during Severe Acute Pancreatitis

  • Matsuhashi Toru
    Department of Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine
  • Kihara Yasuyuki
    Department of Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine
  • Shimada Misa
    Department of Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine
  • Taguchi Masashi
    Department of Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine
  • Tashiro Mitsuo
    Department of Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine
  • Yamamoto Mitsuyoshi
    Department of Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine
  • Otsuki Makoto
    Department of Gastroenterology and Metabolism, University of Occupational and Environmental Health, Japan, School of Medicine

Bibliographic Information

Other Title
  • 重症急性膵炎の発症により大量のインスリンを要した2型糖尿病の1例
  • 症例報告 重症急性膵炎の発症により大量のインスリンを要した2型糖尿病の1例
  • ショウレイ ホウコク ジュウショウ キュウセイスイエン ノ ハッショウ ニ ヨリ タイリョウ ノ インスリン オ ヨウシタ 2ガタ トウニョウビョウ ノ 1レイ

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Abstract

A 63-year-old woman admitted for left hypochondalgia and left back pain on February 27, 2004, had been diagnosed with type 2 diabetes mellitus and treated with oral hypoglycemic agents since 8 years earlier. She was diagnosed with severe acute pancreatitis and treated with a continuous intravenous infusion of rapid insulin. She required 217 units of insulin per day to maintain plasma glucose below 150 mg/dl. The required dose of insulin gradually decreased with improvement of in her condition. Before discharge, her hyperglycemia was successfully controlled with oral hypoglycemic agents without insulin. Hyperglycemia is a risk factor in acute pancreatitis and strict glycemic control plays an important role in improving mortality in severe acute pancreatitis.

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