EFFECTS OF HYPERBARIC OXYGEN THERAPY (HBO) ON RADIATION-INDUCED LATE SEQUELAE
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- MATSUSHITA Haruo
- Fig. 4 Laryngoscopic findings of the patient no. 26, before (a) and after HBO (b).
Bibliographic Information
- Other Title
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- 放射線治療の晩期有害事象に対する高気圧酸素療法についての検討
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Abstract
The objective of our study was to determine the effectiveness of hyperbaric oxygen therapy (HBO) in the treatment of the late sequelae of radiotherapy. We excluded any case in which sequelae were detected and first treated less than three months after the final irradiation. Our study group consisted of 29 patients with the following sub-groups: 8 with osteonecrosis of the mandible & maxilla, 7 with proctocolitis, 7 with hemorrhagic cystitis, 3 with esophageal ulcer, 2 with necrosis of the larynx, 1 with skin ulcer and 1 with radiation medullopathy. We evaluated toxicity grades according to RTOG/EORTC late radiation morbidity scoring scheme before and after HBO in each case, and assessed the effects by comparing these grades. Our findings were showed 5 (17%) of the group had a very good outcome, with reduction of more than two grades, 18 (62%) had a moderate outcome with one grade reduced, while 6 (21%) revealed no change in their level of symptoms. Exacerbation of symptoms was not noted in any case. Since there are few known effective treatments for late toxicity, it is our view that the usefulness of HBO therapy needs to be recognized, and that further studies such as ours should be undertaken.
Journal
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- The Journal of JASTRO
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The Journal of JASTRO 19 (3), 147-155, 2007
Japanese Society for Therapeutic Radiology and Oncology
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Details 詳細情報について
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- CRID
- 1390001204331073664
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- NII Article ID
- 10021282770
- 130004497112
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- NII Book ID
- AN10123988
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- ISSN
- 18819885
- 10409564
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- Text Lang
- ja
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- Data Source
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- JaLC
- CiNii Articles
- KAKEN
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- Abstract License Flag
- Disallowed