コーガン症候群 : MRIで内耳に変化を認めた一例 Magnetic Resonance Imaging in a Patient with Cogan's Syndrome

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著者

    • 小林 泰輔 KOBAYASHI Taisuke
    • 愛媛県立中央病院耳鼻咽喉・頭頸部外科 Department of Otolaryngology Head and Neck Surgery, Ehime Prefectural Central Hospital
    • 岡田 昌浩 OKADA Masahiro
    • 愛媛県立中央病院耳鼻咽喉・頭頸部外科 Department of Otolaryngology Head and Neck Surgery, Ehime Prefectural Central Hospital
    • 中村 光士郎 NAKAMURA Koshiro
    • 愛媛県立中央病院耳鼻咽喉・頭頸部外科 Department of Otolaryngology Head and Neck Surgery, Ehime Prefectural Central Hospital

抄録

Cogan's syndrome is primarily diagnosed based on subsequent episodes of an inflammatory eye disease and rapidly progressive, usually sequential bilateral loss of audiovestibular function. Since there are still no specific tests for the syndrome, it is difficult to diagnose Cogan's syndrome in the early stage before the emergence of both eye and audiovestiubular symptoms. We present a case of a 34-year-old woman who complained of vertigo and bilateral hearing loss. Magnetic resonance imaging (MRI) of the inner ear was performed before the emergence of keratitis. MRI on the 23rd day after onset of hearing loss revealed a slightly high intensity on TI-weighted images in the right vestibule, which showed profound hearing loss. On the 54th day after onset, high signal intensity was noted in the right cochlea, the vestibule, and lateral semicircular canal on Tl-weighted images, but no enhancement. The high signal intensity disappeared seven months after onset, but there was no defect of inner ear signs on the T2-weighted images. A high signal of the inner ear on T1-weighted images is not a specific sign of MRI in Cogan's syndrome, since it is sometimes encountered in the inner ear of labyrinthitis, bleeding in patients with leukemia, and intralabyrinthine schwanoma. However, MRI could be a possible method for the early diagnosis of Cogan's syndrome because this finding might be recognized before the onset of eye symptoms.

収録刊行物

  • Equilibrium research  

    Equilibrium research 65(6), 453-459, 2006-12-01 

    日本めまい平衡医学会

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各種コード

  • NII論文ID(NAID)
    10021289731
  • NII書誌ID(NCID)
    AN00001485
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    03855716
  • データ提供元
    CJP書誌  IR  J-STAGE 
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