Effects of Paroxetine for Vertiginous Patients Associated with Depression

DOI 4 Citations 20 References
  • Ishii Kenji
    Department of Otolaryngology, Hirosaki University School of Medicine Kamio Memorial Hospital
  • Oji Kasumi
    Department of Otolaryngology, Hirosaki University School of Medicine
  • Iida Kenji
    Department of Otolaryngology, Hirosaki University School of Medicine
  • Shinkawa Hideichi
    Department of Otolaryngology, Hirosaki University School of Medicine

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Other Title
  • 抑うつ傾向を伴うめまい症例に対するパロキセチンの効果

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Abstract

Patients with vertigo caused by psychological problems have increased in recent years. It has been reported that many outpatients with vertigo also suffer from depression. Selective serotonin reuptake inhibitors are widely used for the treatment of depression because of their efficacy and relatively favorable side-effects profile compared to those of tricyclic antidepressants. We used Paroxetine to treat patients with vertigo who were diagnosed with depression by self-rating questionnaires for depression (SRQ-D). Twenty-six patients experienced relief after taking Paroxetine. Fifteen of them were relieved of their vertigo symptoms, 8 were improved, one was not changed, and two were worse. SRQ-D scores were compared between the day of commencement and the day after 4 weeks. Fifteen patients were normalized. Side effects occurred in seven patients; nausea in five and sleepiness in two. The average duration of taking the medicine was 24.4 weeks. Since Paroxetine showed beneficial clinical effects for patients with vertigo, this medicine might be useful for vertiginous patients with depression.

Journal

  • Equilibrium Research

    Equilibrium Research 66 (1), 26-30, 2007

    Japan Society for Equilibrium Research

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