長期間メニエール病として加療されていた3症例の検討 [in Japanese] Three Cases Treated for Intractable Meniere's Disease for 7 to 15 Years [in Japanese]
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Three patients suspected of having intractable Meniere's disease had shown no effect via the usual treatment of inner ear hydrops for 7, 13, and 15 years. They were re-evaluated and managed for neurovascular compression syndrome (NVC) of the 8th cranial nerve based on their distinctive vertigo, hearing loss, and tinnitus, followed by symptomatic relief with cinnarizine or a papaverine-containing drug. In addition to these symptoms, two of three patients showed ipsilateral displacement of the basilar artery (BA) on the axial view of MRI.<br>Patients with NVC of the 8th cranial nerve may show rapid relief from sudden onset, recurrent vertigo with severe nystagmus, even in the case of canal paresis, marked fluctuating hearing loss with or without vestibular symptoms, and slowly progressive (unrecognized) hearing loss accompanied by tinnitus of a varying intesity. Patients have experienced symptomatic relief with carbamazepine, cinnatizine, or papaverine-containing drugs.<br>Suspected cases of NVC have shown dolichoectatic ipsilateral convexity of the BA at the level of the internal auditory meatus on the axial view on MRI at a rate of 86.5%, which has been suggested to serve as a diagnostic feature of NVC.
- Equilibrium Res
Equilibrium Res 66(4), 150-155, 2007-08-01
Japan Society for Equilibrium Research