喉頭癌放射線化学療法後に発症した Wernicke 脳症例 A Case of Wernicke's Encephalopathy that Developed after Treatment of Laryngeal Cancer

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A patient with laryngeal cancer had difficulty in eating during radio-chemotherapeutic treatment. Transfusion without vitamins had been given for 40 days, then dizziness on walking and nystagmus developed.<br>Equilibrium function tests showed a saccadic pattern of the ETT, inhibition of the OKP and the reduced caloric responce, but the normal VEMP. Symmetrical high-intensity lesions from the thalamus to the brain stem was observed on MRI-FLAIR.<br>Since Wernicke encephalopathy was suspected, administration of vitamin B<sub>1</sub> was started. Four days later, dizziness improved and appetite was increased. ETT, OKP and MRI findings improved.<br>Although thiamine deficiency in the blood was not proved, Wernicke encephalopathy was highly suspected. The equilibrium function tests and MRI findings suggested a lesion from the thalamus to the abducens nucleus. Thiamine administration improved the symptoms rapidly. It is necessary for undernourished patients to take a vitamin supplements to prevent Wernicke encephalopathy.

収録刊行物

  • 耳鼻咽喉科臨床  

    耳鼻咽喉科臨床 101(3), 179-183, 2008-03-01 

    The Society of Practical Otolaryngology

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各種コード

  • NII論文ID(NAID)
    10021294078
  • NII書誌ID(NCID)
    AN00107089
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00326313
  • NDL 記事登録ID
    9404313
  • NDL 雑誌分類
    ZS43(科学技術--医学--耳鼻咽喉科学)
  • NDL 請求記号
    Z19-421
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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