メチレンブルーを用いた副甲状腺手術 Identification of Parathyroid Glands with Intraoperative Use of Methylene Blue

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Parathyroidectomy (PTx) is the most powerful therapeutic strategy for secondary hyperparathyroidism in patients with chronic renal failure. However, in some cases, identification of pathological parathyroid glands at PTx is not easy, resulting in sustained hyperparathyroidism. In this study, we employed methylene blue dye to discriminate abnormal parathyroid glands in 20 cases during PTx.<br>Methylene blue solution at a dose of 5mg/kg was administered intravenously at the time of skin incision. In 19 of 20 cases (95%), parathyroid glands of various sizes were stained dark blue, whereas the thyroid gland was stained light blue. The dye of the canulated vein as well as pseudohypoxia indicated by pulse oxymetry was observed as a side effect of the dye in most cases as previously reported.<br>Intraoperative infusion of methylene blue could be a useful method of identifying parathyroid glands without any serious side effects. This might provide a beneficial tool to shorten the surgical duration and reduce the incidence of complications following PTx.

収録刊行物

  • 耳鼻咽喉科臨床  

    耳鼻咽喉科臨床 101(3), 221-226, 2008-03-01 

    The Society of Practical Otolaryngology

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各種コード

  • NII論文ID(NAID)
    10021294183
  • NII書誌ID(NCID)
    AN00107089
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00326313
  • NDL 記事登録ID
    9404536
  • NDL 雑誌分類
    ZS43(科学技術--医学--耳鼻咽喉科学)
  • NDL 請求記号
    Z19-421
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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