From cochlear kinematics to cochlear mechanics: matching model to experiments
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- Monvel Jacques Boutet de
- Unité de Génétique des Déficits Sensoriels, Dept. de Neuroscience, Institut Pasteur Center for Hearing and Communication Research, Departments of Clinical Neuroscience and Otolaryngology, Karolinska Institutet
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- Marin Alessandro
- Center for Hearing and Communication Research, Departments of Clinical Neuroscience and Otolaryngology, Karolinska Institutet
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- Jacob Stefan
- Center for Hearing and Communication Research, Departments of Clinical Neuroscience and Otolaryngology, Karolinska Institutet
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- Tomo Igor
- Center for Hearing and Communication Research, Departments of Clinical Neuroscience and Otolaryngology, Karolinska Institutet
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- Tiedemann Miriam von
- Center for Hearing and Communication Research, Departments of Clinical Neuroscience and Otolaryngology, Karolinska Institutet
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- Fridberge Anders
- Center for Hearing and Communication Research, Departments of Clinical Neuroscience and Otolaryngology, Karolinska Institutet
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- Ulfendahl Mats
- Center for Hearing and Communication Research, Departments of Clinical Neuroscience and Otolaryngology, Karolinska Institutet
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- Steele Charles R.
- Departments of Mechanical Engineering, Stanford University
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Abstract
We compare motion patterns of the hearing organ in the apical turn of the guinea pig cochlea, as monitoredby confocal imaging, with motion predicted by a cochlear model including finite element details. Weadjust the model to the angle of view of the images and to the anatomical variability of the organ, by use of aleast-squares method assuming a priori knowledge of the organ's geometry. This approach allows us to fitalso the model's mechanical parameters, based on the motion of the cochlear partition measured under quasistaticchanges of pressure or during sound stimulation. A number of stiffness parameters of the hearingorgan can thus be inferred without placing a physical probe inside the cochlea. This will be useful in buildingcochlear models and in confronting these models with experiments.
Journal
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- Otology Japan
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Otology Japan 17 (2), 76-84, 2007
Japan Otological Society
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Details
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- CRID
- 1390282679746281600
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- NII Article ID
- 10021296849
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- NII Book ID
- AN10358085
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- ISSN
- 18841457
- 09172025
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- Text Lang
- en
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- Data Source
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- JaLC
- CiNii Articles
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- Abstract License Flag
- Disallowed