外耳道・中耳扁平上皮癌における予後因子の検討 Prognostic value of bone involvement in patients with squamous cell carcinoma of the external and middle ear

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著者

    • 志賀 英明 SHIGA Hideaki
    • 金沢大学大学院医学系研究科脳医科学脳病態医学感覚運動病態学 Department of Otorhinolaryngology, Graduate School of Medical Science, Kanazawa University
    • 伊藤 真人 ITO Makoto
    • 金沢大学大学院医学系研究科脳医科学脳病態医学感覚運動病態学 Department of Otorhinolaryngology, Graduate School of Medical Science, Kanazawa University
    • 浦本 直紀 URAMOTO Naoki
    • 金沢大学大学院医学系研究科脳医科学脳病態医学感覚運動病態学 Department of Otorhinolaryngology, Graduate School of Medical Science, Kanazawa University
    • 波多野 都 HATANO Miyako
    • 金沢大学大学院医学系研究科脳医科学脳病態医学感覚運動病態学 Department of Otorhinolaryngology, Graduate School of Medical Science, Kanazawa University
    • 三輪 高喜 MIWA Takaki
    • 金沢大学大学院医学系研究科脳医科学脳病態医学感覚運動病態学 Department of Otorhinolaryngology, Graduate School of Medical Science, Kanazawa University
    • 古川 仭 FURUKAWA Mitsuru
    • 金沢大学大学院医学系研究科脳医科学脳病態医学感覚運動病態学 Department of Otorhinolaryngology, Graduate School of Medical Science, Kanazawa University

抄録

The incidence of the external and middle ear squamous cell carcinoma (SCC) is extremely rare in thehead and neck cancer with less than 1%. Therefore, the correlation between the staging classification and theprognosis has not been clear. Prognostic factors for patients with the external and middle ear SCC wereassessed in the initial clinical symptoms and radiographic imaging. 13 patients with the external and middle ear SCC (5 male and 8 female) that had been treated at the Department of Otorhinolaryngology, Kanazawa University hospital from 2000 to 2006 were selected for this study. The radiation therapy followed surgery inten patients. One patient received the radical cure irradiation before surgery. Two patients received a surgicalexcision alone.<BR>The temporal bone involvement and the parotid gland involvement in the radiographic image (computedtomography imaging and/or magnetic resonance imaging) were assessed. Clinical symptoms (otalgia, hearingdisturbance, tinnitus, vertigo and facial nerve palsy) before treatment were reviewed based on the medicalrecord. The correlation of those clinical factors and T staging in the Pittsburgh classification with overall survivalwas statistically assessed. The temporal bone involvement significantly correlated with worse prognosis. However, parotid gland involvement did not influence the prognosis. Moreover, statistically significant differencein T staging of the Pittsburgh classification (Tl·T2vs. T3·T4) was not found. The temporal boneinvolvement in the radiographic image was a prognostic factor for patients with the external and middle ear SCC. Pittsburgh classification needs to be modified because the bony part of the external auditory canalinvolvement is considered as T2 stage and the soft tissue involvement is defined as T4 stage.

収録刊行物

  • Otology Japan  

    Otology Japan 17(2), 128-132, 2007-05-25 

    THE JAPAN OTOLOGICAL SOCIETY

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各種コード

  • NII論文ID(NAID)
    10021296984
  • NII書誌ID(NCID)
    AN10358085
  • 本文言語コード
    JPN
  • 資料種別
    ART
  • ISSN
    09172025
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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