両側進行性高度難聴を示した骨Paget病の一例

  • 昼間 清
    都立駒込病院耳鼻咽喉科頭頸部腫瘍外科
  • 浅野 貴徳
    千葉大学医学部耳鼻咽喉科頭頸部外科
  • 沼田 勉
    国立病院機構千葉医療センター耳鼻咽喉科

書誌事項

タイトル別名
  • A case of Paget's disease with bilateral progressive hearing loss

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We encountered a patient treated for bilateral sudden deafness, whose hearing level became progressively worse. She showed high alkaline phosphatase activity, high urinary hydroxyproline excretion, and typical temporal bone X-ray findings. Her hearing loss (HL) was a high frequency sensorineural HL and a low frequency air-bone gap. Paget's disease of the bone or fibrous dysplasia was suspected, and a temporal bone biopsy was performed and Paget's disease was diagnosed. Oral alendronate effectively improved her condition.

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