虫垂原発カルチノイド症例の検討 A Clinicopathological Study of Primary Carcinoid Tumor of the Appendix

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著者

    • 柴田 佳久 SHIBATA Y.
    • 豊橋市民病院外科・こう門科 Department of Surgery and Proctology, Toyohashi Municipal Hospital

抄録

消化管に発生するカルチノイド腫瘍は本邦では比較的まれである.当院にて経験した虫垂カルチノイド症例を臨床病理学的に検討した.1996年からの10年間で消化管カルチノイドは74例あり,胃12例·小腸4例·直腸52例·虫垂6例であった.虫垂カルチノイド症例を対象に臨床所見と転帰·病理学的検討を行った.全例女性で平均40.3歳であった.診断契機は虫垂炎手術5例,他の手術時発見1例であった.虫垂切除術のみ3例,追加切除など3例.悪性所見としての深達度はss 5例mp 1例で,脈管侵襲陽性1例,MIB-indexは全例1%以下であった.追加切除では腫瘍の遺残なくリンパ節転移もなかった.全例無再発生存中である.消化管カルチノイドの中で虫垂発生は8%であった.発症は虫垂炎が多く,悪性症例は少なく虫垂切除のみでよいと考えられ,その予後は良好である.<br>

A carcinoid tumor occurring in the alimentary canal is rare in Japan. We reviewed cases of carcinoid tumor occurring in the appendix in our hospital clinicopathologically.<br> Materials and Method: We performed an examination of clinical observations, exitus and pathological study for cases diagnosed as appendiceal carcinoid tumor between 1996 and 2005.<br> Results: Alimentary canal carcinoid tumor was diagnosed in 74 cases during the period: 12 cases in the stomach, 4 cases in the small intestinum, 52 cases in the rectum and 6 cases in the appendix. As for the appendiceal carcinoid tumor cases, the average age was 40.3 years old and all were females. The tumor was found during operation for acute appendicitis (5 cases) and during operation for intestinal disease (one case). The pathological invasion depth of the tumor in the five cases was ss and that of the one case was mp. The malignant potential was low because MIB-index was lower than 1% in all cases. As for the treatment of the tumor, four cases had only an appendectomy and the other two cases had a secondary major operation. Lymph node metastases were not found in the three cases which underwent ileocaecal resection with lymph node dissection. There has been no recurrence in any of the cases.<br> Conclusion: Appendiceal carcinoid tumor appeared in 8% of alimentary canal carcinoid tumors. These cases were mostly diagnosed during acute appendicitis. Most of the appendiceal carcinoid tumors were not malignant and the outcome was good.<br>

収録刊行物

  • 日本大腸肛門病学会雑誌  

    日本大腸肛門病学会雑誌 61(1), 22-26, 2008-01-01 

    The Japan Society of Coloproctology

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キーワード

各種コード

  • NII論文ID(NAID)
    10021302680
  • NII書誌ID(NCID)
    AN00195100
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00471801
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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