Clinicopathological Study on Colorectal Cancer with Recurrence after Curative Surgery According to the Serum Levels of CEA

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  • 術前血清ＣＥＡ値別にみた大腸癌術後再発に関する検討

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Abstract

This study investigated the significance of pre- and postoperative serum CEA level in monitoring colorectal cancer after surgery. The study included 144 colorectal cancer patients with recurrence after curative surgery. Of these, 65 patients with high serum CEA level before surgery (high group) were clinicopathologically compared with 79 patients with serum CEA level within the normal limit (normal group). Hepatic recurrence was detected in 55% of cases by postoperative regular check of serum CEA level and operation was performed in 50% of these cases. Lung recurrence in the high group was found in 58% of cases by postoperative regular check of serum CEA level, but operation was performed in only 21.1% of them. As a result, none of them survived more than 5 years. Local recurrence was found in 56% of cases by symptoms. The regular check of serum CEA level was useful for detection in only 21% of local recurrence cases. Regular check of serum CEA level was thought to be useful in monitoring and detecting hepatic recurrence. It is thought to be important to examine symptoms/signs and to perform regular examinations in monitoring lung and local recurrence.<br>

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