Reliability of Japanese Self-Administered PASI in Clinical Evaluation of Psoriasis and its Relationship to the QOL Related Index

  • Fukuchi Osamu
    Department of Dermatology, The Jikei University School of Medicine
  • Ohta Arihito
    Department of Dermatology, The Jikei University School of Medicine
  • Ishiji Takaoki
    Department of Dermatology, The Jikei University School of Medicine
  • Honda Mariko
    Department of Dermatology, The Jikei University School of Medicine
  • Kamide Ryoichi
    Department of Dermatology, The Jikei University School of Medicine
  • Nakagawa Hidemi
    Department of Dermatology, The Jikei University School of Medicine
  • Komine Mayumi
    Department of Dermatology, The University of Tokyo Hospital
  • Hasegawa Tomonori
    Department of Social Medicine, Toho University School of Medicine

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Other Title
  • 乾癬の臨床評価におけるSelf-Administered PASI の有用性と QOL 指標との関連性
  • カンセン ノ リンショウ ヒョウカ ニ オケル Self Administered PASI ノ ユウヨウセイ ト QOL シヒョウ ト ノ カンレンセイ

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Abstract

In order to evaluate the clinical validity of the self-administered Psoriasis Area and Severity Index (Self-PASI),the patient’s self-reported index for psoriasis severity, we examined associations between Self-PASI and Self-BSA scores with PASI and BSA scores, the physician’s reported index, in 200 Japanese psoriasis patients. Furthermore, we examined the associations between those indices and the psoriasis-specific QOL related index (the Psoriasis Disability Index, PDI) and the comprehensive health-related QOL index (Short Form-36, SF-36). In a results, the correlation coefficients were found to be significant between the patients’ and physicians’ reported indices (0.65 for SAPASI and PASI, 0.69 for Self-BSA and BSA). The correlation coefficients for Self-BSA and BSA were high for the trunk, upper extremities, and lower extremities, but were low for the head. The PDI score has a higher association with Self-PASI and Self-BSA scores than did the PASI and BSA scores. However, compared to the PDI score, the SF-36 score had a lower association with SA-PASI and Self-BSA. In conclusion, the Self-PASI has been shown to be valid and useful in clinical practice for Japanese psoriasis patients.

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