Effects of Type of Diet and Salinomycin Supplementation on Insulin Secretory Response and Action in Sheep

• FUJITA Tadahisa

  Faculty of Agriculture, Iwate University

• ITOH Takahiro

  Faculty of Agriculture, Iwate University

• MAJIMA Hiroya

  Faculty of Agriculture, Iwate University

• SANO Hiroaki

  Faculty of Agriculture, Iwate University

• SHIGA Akio

  Faculty of Agriculture, Iwate University

• AMBO Kaichi

  Faculty of Agriculture, Iwate University

抄録

Hyperglycemic clamp and hyperinsulinemic euglycemic clamp techniques were used to investigate the effects of type of diet and salinomycin supplementation on the insulin secretory response to glucose and tissue responsiveness to insulin in adult sheep. The sheep were fed a high-roughage and a high-concentrate diet at equal energy intakes with or without 20ppm of salinomycin for 3 weeks. Basal plasma glucose concentrations were unaffected by type of diet or salinomycin supplementation in both glucose clamp experiments. The ratio of plasma insulin increments to glucose infusion rates in the hyperglycemic clamp experiment and the glucose infusion rate in the hyperinsulinemic euglycemic clamp experiment were unaffected by type of diet or salinomycin supplementation. Although the number of data was small in the present study, these results suggest that in sheep salinomycin supplementation has no significant effects on either the insulin secretory response to glucose or on insulin action, regardless of type of diet.

収録刊行物

• 日本畜産学会報

  日本畜産学会報 71 (1), 42-49, 2000

  公益社団法人 日本畜産学会

キーワード

• Salinomycin
• Insulin
• Glucose clamp technique
• Sheep

詳細情報

• CRID: 1390282680173727360
• NII論文ID: 10021722058
• NII論文ID: 10020391283
• NII書誌ID: AN00195188
• DOI: 10.2508/chikusan.71.42
• ISSN: 18808255
• ISSN: 00215309
• ISSN: 1346907X
• NDL書誌ID: 4970227
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4970227
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可