正常および下痢発現黒毛和種子牛における末梢血リンパ球幼若化能と血清ハプトグロビンおよびα<sub>1</sub>-酸性糖タンパク質濃度

  • 岡本 光司
    山口大学大学院連合獣医学研究科 鹿児島大学農学部 鹿児島県曽於農業共済組合
  • 原田 道夫
    鹿児島県曽於農業共済組合
  • 阿久沢 正夫
    山口大学大学院連合獣医学研究科 鹿児島大学農学部
  • 出口 栄三郎
    山口大学大学院連合獣医学研究科 鹿児島大学農学部

書誌事項

タイトル別名
  • Peripheral Blood Lymphocyte Blastogenesis and Concentrations of Serum Haptoglobin and α<sub>1</sub>- Acid Glycoprotein in Normal Calves and Calves on the First Onset of Diarrhea
  • セイジョウ オヨビ ゲリ ハツゲン クロゲワシュ コウシ ニ オケル マッショ

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抄録

This experiment was carried out to examine the lymphocyte blastogenesis and concentrations of serum haptoglobin (HP) and α1-acid glycoprotein (α1-AGP) in normal calves and calves on the first onset of diarrhea. Thirty five normal Japanese Black calves and 75 calves with diarrhea caused by rota virus infection, coccidiasis and strongyloides, aged from 3 to 35d, were used. The lymphocyte blastogenesis induced by concanavalin A (ConA; 6.4μg/ml) was determined by a whole blood culture of haparinized-blood and RPMI-1640 medium (1:19) containing 8% fetal calf serum (FCS). The lymphocyte blastogenesis induced by ConA was significantly lower in calves with diarrhea than those in normal calves. The HP was not detected in the sera of all normal calves. However, the serum HP was appeared in 35 of 73 calves with diarrhea (47.9%), showing 262±196mg/l (ranging from 50 to 700mg/l). There was no significant difference in the concentration of serum α1-AGP between the nomlal calves (402±69mg/l) and calves with diarrhea (440±102mg/l). These results show that the lymphocyte function has been decreased and the serum HP can be detected in about one half of the newborn calves on the first onset of diarrhea.

収録刊行物

  • 日本畜産学会報

    日本畜産学会報 69 (7), 683-689, 1998

    公益社団法人 日本畜産学会

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