テラヘルツ波による生体高分子の非標識検出 [in Japanese] Label-Free Detection of Biopolymer Using Terahertz Waves [in Japanese]
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In this paper, we demonstrated two label-free detecting methods of biopolymers. We found that the membrane array which immobilized small molecules was effective for the detection of the protein using THz-TDS imaging system. And a label-free protein sensor, which is based on the resonant transmission phenomenon of a metallic mesh, was proposed in the terahertz wave region. By using this sensor, we demonstrated the highly sensitive detection of small amount of protein and the label-free detecting of biotin-streptavidin or biotin-avidin interactions on a PVDF membrane.
- Bunko Kenkyu
Bunko Kenkyu 57(5), 228-237, 2008-10-15
The Spectroscopical Society of Japan