ICRPのヒト呼吸気道モデル66における生体パラメータがエアロゾル沈着に及ぼす影響 : 日本人とコーカシアン人 Influences of Biometrical Parameters on Aerosol Deposition in the ICRP 66 Human Respiratory Tract Model : Japanese and Caucasians
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In exposure dose assessment, the ICRP (International Commission on Radiological Protection) Publication 66 human respiratory tract model has been used extensively beyond its original purpose which was for radiation protection. The ICRP models are historically based on Caucasians. In this study, the applicability of the ICRP Publication 66 model to Japanese was examined. Aerosol deposition to respiratory tracts was calculated using a computer code, LUDEP (LUng Dose Evaluation Programme) , developed by the NRPB (National Radiological Protection Board), UK. The aerosol deposition efficiencies of Japanese were shown to be almost the same as those of Caucasians. It seemed that there was no problem in the applicability of the ICRP model. But distinctive differences were found in aerosol depositions per person and per body-weight. For example, the maximum deposition per unit time of adult male Japanese in the AI (Alveolar-Interstitial) region at light exercise was approximately 80 % of that of Caucasians.
- Earozoru Kenkyu
Earozoru Kenkyu 22(3), 236-243, 2007-09-20
Japan Association of Aerosol Science and Technology