NASH拾い上げのための簡便なスコアリングシステム (NAFIC score) の提案 A proposal of simple scoring system to differentiate nonalcoholic steatohepatitis from nonalcoholic fatty liver disease : we originally named NAFIC score composed of serum ferritin, fasting insulin, type IV collagen 7S

この論文にアクセスする

この論文をさがす

著者

抄録

Noninvasive, simple, reproducible, and reliable biomarkers are greatly needed to differentiate nonalcoholic steatohepatitis (NASH) from nonalcoholic fatty liver disease (NAFLD). One hundred seventeen patients with biopsy-proven NAFLD were involved in this study. We combined 3 clinical variables to generate the NAFIC score originally: ferritin (≥200 (female) or ≥300 (male) ng/m<i>l</i>), fasting insulin (≥10 μU/m<i>l</i>), and type IV collagen 7S (≥5.0 ng/m<i>l</i>). These parameters were selected as independent variables by multivariate analysis using logistic regression analysis. The presence of each variable gives 1 point in the combined score. The NAFIC score of NASH patients (n=65, 1.94±0.85) was significantly higher than that of simple steatosis patients (n=52, 0.58±0.67, p<0.0001). The percentage of NASH in NAFLD in a total score of 0, 1, 2, and 3 was 10.3% (3/29), 41.0% (16/39), 93.3% (28/30), and 94.7% (18/19), respectively. The NAFIC score can become one of noninvasive, simple, and useful biomarkers to differentiate NASH from NAFLD.<br>

収録刊行物

  • 肝臓 = ACTA HEPATOLOGICA JAPONICA  

    肝臓 = ACTA HEPATOLOGICA JAPONICA 49(6), 279-281, 2008-06-25 

    The Japan Society of Hepatology

参考文献:  5件

参考文献を見るにはログインが必要です。ユーザIDをお持ちでない方は新規登録してください。

各種コード

  • NII論文ID(NAID)
    10021939019
  • NII書誌ID(NCID)
    AN00047770
  • 本文言語コード
    JPN
  • 資料種別
    SHO
  • ISSN
    04514203
  • NDL 記事登録ID
    9546614
  • NDL 雑誌分類
    ZS21(科学技術--医学--内科学)
  • NDL 請求記号
    Z19-130
  • データ提供元
    CJP書誌  NDL  J-STAGE 
ページトップへ