A case of Child-Pugh class B cirrhosis in hepatitis C infection successfully treated with interferon beta after balloon-occluded retrograde transvenous obliteration for gastric varices

• Sato Akira

  Division of Gastroenterology, Saint Marianna University Yokohama City Seibu Hospital

• Adachi Kayo

  Division of Gastroenterology, Saint Marianna University Yokohama City Seibu Hospital

• Ishii Toshiya

  Division of Gastroenterology, Saint Marianna University Yokohama City Seibu Hospital

• Yamaguchi Masayo

  Division of Gastroenterology, Saint Marianna University Yokohama City Seibu Hospital

• Kobayashi Mika

  Division of Gastroenterology, Saint Marianna University Yokohama City Seibu Hospital

• Hayashi Mikihito

  Division of Gastroenterology, Saint Marianna University Yokohama City Seibu Hospital

• Tabashi Miyako

  Division of Gastroenterology, Saint Marianna University Yokohama City Seibu Hospital

• Nomoto Masahito

  Division of Gastroenterology, Saint Marianna University Yokohama City Seibu Hospital

• Nikai Akira

  Division of Gastroenterology, Saint Marianna University Yokohama City Seibu Hospital

Bibliographic Information

Other Title

• 胃静脈瘤の治療後にインターフェロン療法を施行し著効が得られたＣｈｉｌｄ－Ｐｕｇｈ　ｃｌａｓｓ　ＢのＣ型肝硬変の１例
• 症例報告 胃静脈瘤の治療後にインターフェロン療法を施行し著効が得られたChild-Pugh class BのC型肝硬変の1例
• ショウレイ ホウコク イ ジョウミャクリュウ ノ チリョウゴ ニ インターフェロン リョウホウ オ シコウシ チョコウ ガ エラレタ Child Pugh class B ノ Cガタ カンコウヘン ノ 1レイ

Abstract

Sustained virological response was achieved by interferon beta treatment in a case of hepatitis C virus (HCV) cirrhosis with a Child-Pugh score of 8 and gastric varices. A 52-year-old man with cirrhosis due to HCV-genotype 2a and low viral load underwent balloon-occluded retrograde transvenous obliteration for F3 gastric varices. Although mild jaundice remained, his percent prothrombin time improved from 55.3% to more than 70% after treatment, and he was given interferon beta for 32 weeks. One year after interferon treatment, serum HCV-RNA is negative and Child-Pugh score has decreased to 5 as a result of improved jaundice. Interferon therapy should be considered, even in patients with advanced HCV cirrhosis and portal hypertension, if the patient has HCV-genotype 2 and low viral load.<br>

Journal

• Kanzo

  Kanzo 49 (7), 307-313, 2008

  The Japan Society of Hepatology

Keywords

• chronic hepatitis C
• compensated cirrhosis
• Child-Pugh score
• interferon
• gastric varices

Details

• CRID: 1390001204793397632
• NII Article ID: 10021939135
• NII Book ID: AN00047770
• DOI: 10.2957/kanzo.49.307
• ISSN: 18813593
• ISSN: 04514203
• NDL BIB ID: 9585503
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I9585503
• Web Site: http://www.jstage.jst.go.jp/article/kanzo/49/7/49_7_307/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2008288318
• Text Lang: ja
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed