A case of acute hepatitis C, most likely by interspousal sexual transmission after 40 years of marriage
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- Aikawa Tatsuya
- Aikawa Internal Medicine Hospital
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- Kojima Maki
- Aikawa Internal Medicine Hospital
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- Miyamoto Kuniko
- Aikawa Internal Medicine Hospital
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- Ueno Chisato
- Aikawa Internal Medicine Hospital
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- Takahashi Masaharu
- Division of Virology, Department of infection and Immunity, Jichi Medical University School of Medicine
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- Okamoto Hiroaki
- Division of Virology, Department of infection and Immunity, Jichi Medical University School of Medicine
Bibliographic Information
- Other Title
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- 結婚40年後の配偶者間性行為感染が疑われたC型急性肝炎の1例
- 症例報告 結婚40年後の配偶者間性行為感染が疑われたC型急性肝炎の1例
- ショウレイ ホウコク ケッコン 40ネンゴ ノ ハイグウシャカン セイコウイ カンセン ガ ウタガワレタ Cガタ キュウセイ カンエン ノ 1レイ
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Abstract
A 67-year-old man contracted acute hepatitis C after 40 years of marriage, who had no discernible risk factors for acquiring hepatitis C virus (HCV) infection, except that he had a monogamous sexual relationship (once or twice a month) with his wife with chronic hepatitis C who was infected with HCV of the same genotype (1b) and had a high-titer HCV RNA in the serum (>5,000 KIU/ml). The HCV isolates from the patient and his wife shared 99.7% identity in the 1,087 nucleotide (nt) sequence of the NS5B region, although these two isolates were only 96.7% identical to the 98 reported genotype 1b isolates. Phylogenetic analysis of the 1,087-nt sequence revealed that the two isolates segregated into a cluster with a bootstrap value of 100%. These results suggest that the patient had acquired HCV infection from his wife, most likely by interspousal sexual transmission.<br>
Journal
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- Kanzo
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Kanzo 49 (8), 352-361, 2008
The Japan Society of Hepatology
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Details
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- CRID
- 1390282679772198528
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- NII Article ID
- 10021939311
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- NII Book ID
- AN00047770
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- ISSN
- 18813593
- 04514203
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- NDL BIB ID
- 9620355
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- Crossref
- CiNii Articles
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- Abstract License Flag
- Disallowed