Miller Fisher 症候群例 A Case of Miller-Fisher Syndrome

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The Miller-Fisher syndrome (MFS) is clinically defined by the triad of ataxia, areflexia and ophthalmoplegia. The pathophysiology of MFS involves immunologically mediated central and peripheral processes. We report a thirty-three-year-old male patient with Miller-Fisher syndrome. He initially manifested diarrhea two weeks before onset. He was referred to our clinic with dizziness, double vision and reduced left hand sensation. Physical examination on admission showed diminished eye movements in external directions, areflexia and ataxia. Findings on brain magnetic resonance imaging (MRI) and cerebrospinal fluid (CFS) examination were unremarkable. We analyzed the eye movement using electro-nystagmograph, and mild brainstem dysfunction was indicated. Anti-GQ1b antibody was positive in the serum. Thus, we diagnosed this patient as having MFS. Symptoms and neurological dysfunction improved gradually without treatment during the following weeks, and there were no sequelae.

収録刊行物

  • 耳鼻咽喉科臨床  

    耳鼻咽喉科臨床 101(9), 655-662, 2008-09-01 

    The Society of Practical Otolaryngology

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各種コード

  • NII論文ID(NAID)
    10021941041
  • NII書誌ID(NCID)
    AN00107089
  • 本文言語コード
    JPN
  • 資料種別
    NOT
  • ISSN
    00326313
  • NDL 記事登録ID
    9635706
  • NDL 雑誌分類
    ZS43(科学技術--医学--耳鼻咽喉科学)
  • NDL 請求記号
    Z19-421
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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