Circadian Variations of Salivary Stress Marker (Chromogranin A)

この論文にアクセスする

この論文をさがす

著者

    • MAKINO Michiko
    • Department of Oral Reconstruction and Rehabilitation, Kyushu Dental College
    • MASAKI Chihiro
    • Department of Oral Reconstruction and Rehabilitation, Kyushu Dental College
    • TOMOEDA Kei
    • Department of Oral Reconstruction and Rehabilitation, Kyushu Dental College
    • TAKENAKA Megumi
    • Department of Oral Reconstruction and Rehabilitation, Kyushu Dental College
    • KOJO Tatsuro
    • Department of Oral Reconstruction and Rehabilitation, Kyushu Dental College
    • MURAKAMI Shigeki
    • Department of Oral Reconstruction and Rehabilitation, Kyushu Dental College
    • HOSOKAWA Ryuji
    • Department of Oral Reconstruction and Rehabilitation, Kyushu Dental College

抄録

Bruxism is a very common parafunction of the masticatory system. Currently, there is consensus about the multifactorial nature of the etiology of bruxism, and it is thought to be a central nervous system phenomenon related to stress and pain behavior rather than structural components. The relationship of bruxism and subjective stress has remained unclear. Recently, biomarkers have been used for assessing stress reaction such as chromogranin A (CgA) and cortisol. The level of CgA provides a sensitive and reliable index for evaluating psychological stress. We can have many reports about plasma CgA, but we can't have enough reports about salivary CgA. The aim of this study was to clarify circadian variation CgA in saliva. Four adults (1 male, 3 females) participated in this research. Subjects provided ten saliva samples. Saliva samples were collected in the morning (9 am) and in the night (21 pm), and every 3 h for 24 h. In addition, saliva samples were two-minute stimulated and unstimulated samples to measure CgA concentration, major salivary stress biomarkers. Unstimulated salivary CgA concentration varied more in time and individual difference than stimulated. Stimulated salivary CgA concentration was increased from 12 pm to 18 pm. Salivary CgA seemed to have a circadian variation with peak in the afternoon-night period and a nadir in the noon. With regard to circadian variations, salivary CgA concentrations, in particular stimulated saliva, hardly differ from plasma CgA. It was concerned that CgA concentration was influenced from a lot of factors.

収録刊行物

  • Prosthodontic research & practice  

    Prosthodontic research & practice 7(2), 189-191, 2008-07-01 

    Japan Prosthodontic Society

参考文献:  7件

参考文献を見るにはログインが必要です。ユーザIDをお持ちでない方は新規登録してください。

被引用文献:  1件

被引用文献を見るにはログインが必要です。ユーザIDをお持ちでない方は新規登録してください。

各種コード

  • NII論文ID(NAID)
    10021955212
  • NII書誌ID(NCID)
    AA11728086
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13477021
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
ページトップへ