Adhesion of C. albicans to Acrylic Resin Containing Fluoridated Apatite-Coated TiO_2

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著者

    • SAWADA Tomofumi
    • Division of Removal Prosthetics, Department of Oral and Maxillofacial Rehabilitation, Kanagawa Dental College
    • KIMOTO Katsuhiko
    • Division of Fixed Prosthodontics, Department of Oral and Maxillofacial Rehabilitation, Kanagawa Dental College
    • TAKAHASHI Yusuke
    • Division of Microbiology, Department of Infection Control, Kanagawa Dental College
    • SAWADA Tomoji
    • Division of Removal Prosthetics, Department of Oral and Maxillofacial Rehabilitation, Kanagawa Dental College
    • HAMADA Nobushiro
    • Division of Microbiology, Department of Infection Control, Kanagawa Dental College
    • SHIBATA Takeshi
    • Division of Fixed Prosthodontics, Department of Oral and Maxillofacial Rehabilitation, Kanagawa Dental College
    • HORI Norio
    • Division of Fixed Prosthodontics, Department of Oral and Maxillofacial Rehabilitation, Kanagawa Dental College
    • AOKI Hiromichi
    • Division of Fixed Prosthodontics, Department of Oral and Maxillofacial Rehabilitation, Kanagawa Dental College
    • NONAMI Toru
    • Division of Removal Prosthetics, Department of Oral and Maxillofacial Rehabilitation, Kanagawa Dental College
    • TOYODA Minoru
    • Division of Removal Prosthetics, Department of Oral and Maxillofacial Rehabilitation, Kanagawa Dental College

抄録

Purpose: This study investigated the inhibitory effect of acrylic resin incorporating FAp-TiO<sub>2</sub> against the adhesion of C. albicans.<br>Materials and methods: FAp-TiO<sub>2</sub> was added at 1, 5, 10 wt% to acrylic resin to form specimen disks of 7 mm diameter, and the surface roughness was measured. Then, C. albicans was cultured aerobically at 37 °C for 24 hours in glucose peptone yeast extract (GPY) broth, and adjusted to OD=1 at 550 nm with a KCl-buffer. The disks were immersed in the C. albicans suspension for 2 hours at 37 °C with UVA from a black light source. After the incubation, the disks were washed gently with phosphate buffer saline (PBS), and the luminescent signal derived from the viable cells on the disks was determined using a bioluminescence adenosine triphosphate (ATP) assay.<br>Results: In the measurement of surface roughness, no significant difference was observed between any of the specimens. The adhesion assay of C. albicans revealed that a statistically significant decrease was observed in FAp-TiO<sub>2</sub> when compared with the control (p‹0.01).<br>Conclusion: We suggest that acrylic resin incorporating FAp-TiO<sub>2</sub> prevents the adhesion of C. albicans, indicating a wide range of possibilities for the practical use of new photocatalysts in acrylic resin.

収録刊行物

  • Prosthodontic research & practice  

    Prosthodontic research & practice 7(2), 201-203, 2008-07-01 

    Japan Prosthodontic Society

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各種コード

  • NII論文ID(NAID)
    10021955243
  • NII書誌ID(NCID)
    AA11728086
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13477021
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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