Development of Oligodendrocyte and Myelination in the Central Nervous System

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著者

    • 阿相 皓晃 ASOU Hiroaki
    • Department of Physiology School of Medicine, Keio University Department of Physiology, School of Medicine, Keio University
    • 戸田 正博 TODA Masahiro
    • Department of Physiology School of Medicine, Keio University Department of Physiology, School of Medicine, Keio University

抄録

We demonstrated the cell lineage of oligodendrocytes from the glial precursor cells to mature oligodendrocytes forming myelin sheath around the axon. There are several different stages of oligodendrocyte development <i>in vito</i>. So far there are no precise data about their morphological changes during oligodendrocyte development, but by the analysis using SEM and immunostaining, the characteristic morphological changes with serial expression of cell markers were observed in each developmental steps of oligodendrocyte. We have also clearly demonstrated how oligodendrocytes wrap around the axon by using video time-lapse movies. These results will be useful for understanding the exact cellular mechanism of myelination in the CNS.

収録刊行物

  • Keio journal of medicine  

    Keio journal of medicine 44(2), 47-52, 1995-06-01 

    The Keio Journal of Medicine

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各種コード

  • NII論文ID(NAID)
    10021984820
  • NII書誌ID(NCID)
    AA00710216
  • 本文言語コード
    ENG
  • 資料種別
    REV
  • ISSN
    00229717
  • データ提供元
    CJP書誌  CJP引用  J-STAGE 
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