Ventricular Arrhythmias in Heart Failur.

• 三田村 秀雄

  Department of Medicine, School of Medicine, Keio University

抄録

In the management of patients with chronic heart failure, our attention is shifting from just improving left ventricular function and abolishing ventricular arrhythmias to improving personal longevity. Importantly, sudden cardiac death is a pattern of death in as many as a half of patients with chronic heart failure. Arrhythmias are common in this disorder, but may possibly be a marker of diseased heart rather than a predictor of sudden cardiac death. The mechanisms and triggers of rapid ventricular tachycardia or fibrillation responsible for sudden cardiac death have not been well established. At present, it is important to be reminded that pharmacologic augmentation of cardiac contractility or suppression of asymptomatic ventricular arrhythmias is not an effective approach to preventing sudden cardiac death, but may even be deleterious. Three groups of drugs that have shown efficacy in preventing sudden cardiac death in patients with chronic heart failure are amiodarone, beta-blockers, and angiotensin-converting enzyme (ACE) inhibitors. Although how these drugs improve prognosis of heart failure are not clear at present, myocardial protection by these agents appears to be most important.

収録刊行物

• Ｔｈｅ　Ｋｅｉｏ　Ｊｏｕｒｎａｌ　ｏｆ　Ｍｅｄｉｃｉｎｅ

  Ｔｈｅ　Ｋｅｉｏ　Ｊｏｕｒｎａｌ　ｏｆ　Ｍｅｄｉｃｉｎｅ 45 (1), 1-8, 1996

  The Keio Journal of Medicine

キーワード

• ventricular arrhythmia
• heart failure
• sudden death
• antiarrhythmic drug

詳細情報

• CRID: 1390282681312038784
• NII論文ID: 10021985393
• NII書誌ID: AA00710216
• DOI: 10.2302/kjm.45.1
• ISSN: 18801293
• ISSN: 00229717
• PubMed: 8882462
• Web Site: https://www.jstage.jst.go.jp/article/kjm1952/45/1/45_1_1/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/1997039223
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可