脳性麻痺児の下肢痙縮に対するＡ型ボツリヌス毒素療法の試み

DOI PubMed 被引用文献2件 参考文献20件
  • 根津 敦夫
    横浜市立大学附属市民総合医療センター小児医療センター
  • 市川 和志
    横浜市立大学附属市民総合医療センター小児医療センター
  • 武下 草生子
    横浜市立大学附属市民総合医療センター小児医療センター

書誌事項

タイトル別名
  • Preliminary Trial of Botulinum Toxin A Therapy for Lower Extremity Spasticity in Children with Cerebral Palsy

この論文をさがす

抄録

Eleven children with gait disturbance due to cerebral palsy (mean age, 5.6 years, ranging from 2.4 to 11.5) were treated with Botulinum toxin A (BTA, BOTOX Allergan) for improvement of spasticity and walking difficulty. BTA was injected into the gastrocnemius, adductors, and hamstring muscles with an initial total dose up to 8 units/kg or 100 units. Spasticity and gait disturbance were significantly improved in all patients 4 weeks after the treatment. Their parents also reported that BTA was helpful for brace tolerance and assistance of caregivers. No side effects including worsening of gait or signs of systemic adverse effects were observed. Management of leg spasticity with BTA is thought to be useful and safe, and approval for this use in Japan is recommended.

収録刊行物

  • 脳と発達

    脳と発達 40 (1), 15-19, 2008

    THE JAPANESE SOCIETY OF CHILD NEUROLOGY

被引用文献 (2)*注記

もっと見る

参考文献 (20)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ