An autopsy case of adenosquamous carcinoma of the pancreas producing granulocyte-colony stimulating factor (G-CSF)

• AKAIKE Hidenori

  First Department of Surgery, University of Yamanashi, School of Medicine

• ITAKURA Jun

  First Department of Surgery, University of Yamanashi, School of Medicine

• OHSAWA Toshiya

  First Department of Surgery, University of Yamanashi, School of Medicine

• FUJII Hideki

  First Department of Surgery, University of Yamanashi, School of Medicine

• NAKAZAWA Tadao

  Department of Human Pathology, University of Yamanashi, School of Medicine

• MURATA Shinichi

  Department of Human Pathology, University of Yamanashi, School of Medicine

• KATOH Ryouhei

  Department of Human Pathology, University of Yamanashi, School of Medicine

Bibliographic Information

Other Title

• Ｇｒａｎｕｌｏｃｙｔｅ－ｃｏｌｏｎｙ　ｓｔｉｍｕｌａｔｉｎｇ　ｆａｃｔｏｒ（Ｇ－ＣＳＦ）産生膵腺扁平上皮癌の１剖検例

Abstract

A 78-year-old woman visited the hospital because of high fever. The peripheral leukocyte count was very high. An abdominal CT revealed tumors in the pancreatic tail and both lobes of the liver. Liver abscess was suspected for persistent fever, but pus and bacteria were not found from puncture and drainage of the liver tumor. On the other hand, adenosquamous carcinoma was revealed in this site. According to these findings the patient was diagnosed as adenosquamous carcinoma of the pancreas with multiple liver metastases. Systemic chemotherapy was scheduled but it could not be performed because infectious disease was suspected by blood culture. The patient died 41 days after admission. High serum levels of granulocyte-colony stimulating factor(G-CSF) persisted and immunohistochemical staining of the autopsy section showed that the pancreatic cancer cells were positive for G-CSF only in the adenocarcinoma portion. The final diagnosis was adenosquamous carcinoma of the pancreas producing G-CSF.<br>

Journal

• Suizo

  Suizo 23 (4), 494-500, 2008

  Japan Pancreas Society

Keywords

• Granulocyte-colony stimulating factor producing tumor
• Pancreatic cancer
• Adenosquamous carcinoma

Details

• CRID: 1390001204638713728
• NII Article ID: 130004495813
• NII Article ID: 10024367783
• NII Book ID: AN10043798
• DOI: 10.2958/suizo.23.494
• ISSN: 18812805
• ISSN: 09130071
• Web Site: https://search.jamas.or.jp/link/ui/2008319840
• Text Lang: ja
• Data Source:
  • JaLC
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed