Novel Biodegradable Copoly(amino acid)s Based on 6-Aminocaproic Acid and <scp>l</scp>-Proline

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  • Weipeng Zhang
    School of Materials Science and Engineering, State Key Laboratory for Mechanical Behavior of Materials, Xi’an Jiaotong University

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<jats:title>Abstract</jats:title> <jats:p>Novel biodegradable copoly(amino acid)s based on 6-aminocaproic acid and l-proline were prepared by melt polycondensation and characterized by IR and 1H NMR. They showed high mechanical properties with high viscosity ranging from 0.72 to 1.70 dL/g. Enzymatic degradation showed that with increasing proline content the enzymatic degradation rate of the copolymers increased. The cellular interaction of copolymer films and HEK 293 cells was observed using SEM; cells adhered and spread well on the material surfaces.</jats:p>

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  • Chemistry Letters

    Chemistry Letters 37 (11), 1142-1143, 2008-10-11

    Oxford University Press (OUP)

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