Creations of biological Pacemaker

• Narazaki Genta

  Laboratory of Stem Cell Differentiation, Stem Cell Research Center, Institute for Frontier Medical Sciences, Kyoto University, Kyoto, Japan

• Yamashita Jun K.

  Center for iPS Cell Research and Application (CiRA), Institute for Integrated Cell-Material Sciences (iCeMS), Kyoto University, Kyoto, Japan

抄録

The heart is one of the most important targets of regenerative medicine. The pacemaker, which controls the rate of beating, is also a target of regeneration. Until today, various researches have been aiming at generating biological pacemakers, but there are only a few reports about detailed analyses of candidates of cells for a really functional pacemaker. Recently, we reported novel induction methods of spontaneous beating cardiomyocytes from mouse embryonic stem (ES) cells, and detailed analysis of ion channel dynamics during their differentiation. This review briefly overviews up to date researches about biological pacemaker and our results achieved recently.

収録刊行物

• Inflammation and Regeneration

  Inflammation and Regeneration 29 (2), 123-127, 2009

  一般社団法人 日本炎症・再生医学会

キーワード

• embryonic stem cell
• induced pluripotent stem cell
• pacemaker
• regeneration
• sino-atrial node

詳細情報

• CRID: 1390001205257287168
• NII論文ID: 10024797269
• NII書誌ID: AA11508953
• DOI: 10.2492/inflammregen.29.123
• ISSN: 18808190
• ISSN: 18809693
• NDL書誌ID: 10248646
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10248646
• Web Site: https://search.jamas.or.jp/link/ui/2009251623
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可