本邦初の妊婦に於ける３型土着株によるＥ型肝炎

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タイトル別名
  • A first case of pregnant woman who contracted infection of indigenous genotype 3 hepatitis E virus in Japan
  • ホンポウ ハツ ノ ニンプ ニ オケル 3ガタ ドチャクカブ ニ ヨル Eガタ カンエン

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A 35-year-old woman who was 14 weeks pregnant visited a gynecology hospital to undergo a surgical abortion. Although she was not jaundiced, and had no signs of hepatitis, liver function was abnormal (ALT, 100 IU/L; AST, 96 IU/L). The serum obtained was negative for markers of hepatitis A, B, and C viruses. However, based on the positive results of non-routine IgM/IgA anti-HEV and HEV RNA assays, the patient was occasionally diagnosed with sporadic acute hepatitis E. The HEV isolate recovered from the patient was phylogenetically close to known genotype 3 HEV strains circulating in Japan, with the highest identity of 93.2%. We believe that testing for hepatitis E should be routine in Japan, in cases of suspected viral hepatitis.<br>

収録刊行物

  • 肝臓

    肝臓 50 (3), 163-165, 2009

    一般社団法人　日本肝臓学会

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