りんご枝おが屑を利用した鹿角霊芝の脂質代謝調節作用  [in Japanese] Regulative Functions of Lipid Metabolism by Dietary Antlered Form of Ganoderma lucidum Using Sawdust of Apple Branch as Medium in Rats  [in Japanese]

5週齢Sprague-Dawly（SD）系雄ラットに0.5％コレステロールと5％りんご鹿角霊芝（AAFGL）を含む飼料を14日間与え，AAFGLによる脂質代謝調節作用を検証した．その結果，AAFGL投与ラットでは，白色脂肪組織重量が対照群と比べて減少する傾向にあった．血圧はAAFGL摂取で対照群よりも低くなり，血液流動性はAAFGL摂取群が対照群よりも良い傾向にあった．肝臓と血清総コレステロール濃度は対照群と比べてAAFGL摂取で低下する傾向にあった．血清HDL−コレステロール濃度は対照群と比べて有意に上昇し，AAFGL群の動脈硬化指数は有意に低下した．肝臓トリグリセリド濃度はAAFGL摂取により低下する傾向にあった．糞中の酸性と中性ステロイド排泄量は対照群よりもAAFGL群が増加傾向を示した．このように，AAFGLは肥満予防作用ならびに脂質代謝調節作用を示す可能性が示唆された．

The regulative effects of lipid metabolism by the dietary antlered form of Ganoderma lucidum (AAFGL) using sawdust of an apple branch as a medium were studied in rats fed 0.5% cholesterol. Male Sprague-Dawly (SD) rats (5 weeks old, n=6-7 per group) were divided into control and 1% AAFGL groups. Rats were given test diets for 14 days. In the AAFGL group, the weight of white adipose tissue tended to be lower, blood pressure was decreased and blood flow velocity tended to be faster. Moreover, the levels of liver and serum cholesterol tended to be lower in the AAFGL group, but the level of serum HDL-cholesterol was significantly higher, indicating that the atherosclerotic index in the AAFGL group was significantly decreased compared with the control. In addition, dietary AAFGL lowered the liver triglyceride level and there was a slight increase in the excretion of neutral and acidic steroids in the feces of the AAFGL group. Thus, dietary AAFGL may exert a preventive function against obesity and a regulative function of lipid metabolism.