化学放射線療法後の救済手術の現状と問題点―特にPlanned Neck Dissectionについて―

  • 河本 勝之
    鳥取大学医学部感覚運動医学講座耳鼻咽喉・頭頸部外科学分野
  • 片岡 英幸
    鳥取大学医学部感覚運動医学講座耳鼻咽喉・頭頸部外科学分野
  • 竹内 英二
    鳥取大学医学部感覚運動医学講座耳鼻咽喉・頭頸部外科学分野
  • 藤原 和典
    鳥取大学医学部感覚運動医学講座耳鼻咽喉・頭頸部外科学分野
  • 中村 陽祐
    鳥取大学医学部感覚運動医学講座耳鼻咽喉・頭頸部外科学分野
  • 三宅 成智
    鳥取大学医学部感覚運動医学講座耳鼻咽喉・頭頸部外科学分野

書誌事項

タイトル別名
  • Planned neck dissection after concurrent chemo-radiotherapy for advanced head and neck cancer
  • ―特にPlanned Neck Dissectionについて―

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抄録

Advanced head and neck cancer patients who select concurrent chemo-radiotherapy (CCRT) have increased because they aspire to preserve their organ and function. We carried out CCRT and planned neck dissection (PND) after CCRT because of a high rate of regional failure of CCRT. However, at the salvage operation including PND, severe complications and functional disorder occurred and lasted for a long time. We examined the problems and therapeutic effects of PND after CCRT in about 14 advanced cancer patients of N2b, N2c and N3. In the pathology of specimens, viable cancer cells were observed in 4 cases (29%) and absence of viable cancer cells in 10 cases (71%). The overall complication rate was 8/14 (57%); postoperative bleeding (3 cases), lymphatic fistula (2), foundation infections (1) and dysphagia (3). All the patients survived after CCRT and PND, neck failure occurred in 2 cases (14%) and lung metastasis in 2 cases (14%). In conclusion, PND after CCRT can be an alternative treatment for advanced head and neck cancer. We have to carefully carry out the PND to avoid complications related to such procedures.

収録刊行物

  • 頭頸部外科

    頭頸部外科 18 (1), 13-19, 2008

    特定非営利活動法人 日本頭頸部外科学会

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