進行性難聴を呈したＰ‐ＡＮＣＡ陽性Ｗｅｇｅｎｅｒ肉芽腫症

DOI Web Site 被引用文献6件 参考文献28件
  • 坂口 博史
    京都府立医科大学耳鼻咽喉科・頭頸部外科学教室
  • 任 書晃
    京都府立医科大学耳鼻咽喉科・頭頸部外科学教室
  • 瀧 正勝
    京都府立医科大学耳鼻咽喉科・頭頸部外科学教室
  • 鈴木 敏弘
    京都府立医科大学耳鼻咽喉科・頭頸部外科学教室
  • 久 育男
    京都府立医科大学耳鼻咽喉科・頭頸部外科学教室

書誌事項

タイトル別名
  • A Case of P-ANCA Positive Wegener's Granulomatosis with Progressive Hearing Loss
  • 臨床 進行性難聴を呈したP-ANCA陽性Wegener肉芽腫症
  • リンショウ シンコウセイ ナンチョウ オ テイシタ P ANCA ヨウセイ Wegener ニクゲシュショウ

この論文をさがす

抄録

We report a case of P-ANCA positive Wegener’s granulomatosis (WG) with progressive hearing loss. A 63-year-old woman consulted a hospital complaining of right hearing loss. While she received therapy under diagnosis of sudden deafness, she developed a right facial nerve palsy and branch retinal artery occlusion. She was diagnosed as having WG based on specific symptoms in the upper respiratory tract (otitis and sinusitis), pathological findings in the nasal mucosa and blood test data including positive findings for P-ANCA. After she achieved remission induction with corticosteroid and immunosuppressant administration, hearing improved markedly and P-ANCA turned negative. Six years after remission, she demonstrated combined hearing loss in her left ear. Five years later, hearing loss in the left ear progressed acutely. Hearing loss was partially improved by medication at each episode, but has generally progressed during the past eleven years. The long-term clinical course showed that the titer of P-ANCA increased several months prior to the exacerbation of the hearing loss and coincidentally became negative with hearing improvement. This case provides a clinical example showing that P-ANCA can be used as an early marker for disease progression in P-ANCA-positive WG.<br>

収録刊行物

被引用文献 (6)*注記

もっと見る

参考文献 (28)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ