Design and Fabrication of Biosensor Device by Use of Receptor Proteins

• Kuwana Yoshihiko

  National Institute of Agrobiological Sciences

• Kojima Katsura

  National Institute of Agrobiological Sciences

• Tamada Yasushi

  National Institute of Agrobiological Sciences

抄録

We have been studying a new type of biosensor that uses and mimics sensory functions of insects. The biosensor can be characterized in combination with immobilized signal transduction biomolecules, i.e., receptor proteins, and a semiconductor device as a transducer. We have developed a lipid bilayer membrane for receptor immobilization and combined it with an insulated-gate field-effect transistor (IGFET). By using this bilayer-IGFET device, we have measured changes in the bilayer membrane potential after introducing α-hemolysin, which acts as a model of receptors. This indicates that the developed device could be used for the biosensor using receptor proteins.

収録刊行物

• 電気学会論文誌Ｅ（センサ・マイクロマシン部門誌）

  電気学会論文誌Ｅ（センサ・マイクロマシン部門誌） 129 (10), 317-320, 2009

  一般社団法人 電気学会

キーワード

• Biosensor
• Receptor proteins
• Lipid bilayer membrane
• Insulated-gate field-effect transistor
• Silk moth

詳細情報

• CRID: 1390001204461667328
• NII論文ID: 10025318981
• NII書誌ID: AN1052634X
• DOI: 10.1541/ieejsmas.129.317
• ISSN: 13475525
• ISSN: 13418939
• NDL書誌ID: 10451106
• Web Site: http://id.ndl.go.jp/bib/10451106
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I10451106
• Web Site: http://www.jstage.jst.go.jp/article/ieejsmas/129/10/129_10_317/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可