A case of well-differentiated cholangiolocellular carcinoma visualized with contrast-enhanced ultrasonography using Sonazoid

• JOSHITA Satoru

  Department of Internal Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine

• ICHIJO Tetsuya

  Department of Internal Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine

• SUZUKI Fumitaka

  Department of Surgery, Shinshu University School of Medicine

• YOKOYAMA Takahide

  Department of Surgery, Shinshu University School of Medicine

• SUGIYAMA Yukiko

  Department of Radiology, Shinshu University School of Medicine

• FUKUSHIMA Mana

  Department of Laboratory Medicine, Shinshu University School of Medicine

• KAMIJO Atsushi

  Department of Internal Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine

• KOMATSU Michiharu

  Department of Internal Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine

• UMEMURA Takeji

  Department of Internal Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine

• YOSHIZAWA Kaname

  Department of Internal Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine

• MIYAGAWA Shinichi

  Department of Surgery, Shinshu University School of Medicine

• TANAKA Eiji

  Department of Internal Medicine, Division of Gastroenterology and Hepatology, Shinshu University School of Medicine

抄録

We here report the first case of cholangiolocellular carcinoma (CoCC) visualized with contrast-enhanced ultrasonography (CEUS) using a second-generation contrast agent, Sonazoid. A 76-year-old man was admitted to our hospital for evaluation of a hepatic tumor. The tumor was described as having hyper-enhancement in the early phase and persistent enhancement in the late phase by contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI), as well as hypervascularity by angiography. CEUS assessment of the nodule showed diffuse and homogeneous enhancement in the pure arterial phase, which became progressively hypoechoic relative to the adjacent liver parenchyma during the portal vein and late phases (mixed vascular phase), and showed a contrast defect with an unclear border in the Kupffer phase. Histologically we diagnosed this hepatic tumor as CoCC. In light of the above findings and the rarity of CoCC, it is helpful to incorporate the results of several imagings, such as CT, MRI, angiography and CEUS with a second-generation contrast agent when clinically diagnosing CoCC.

収録刊行物

• Hepatology research : the official journal of the Japan Society of Hepatology

  Hepatology research : the official journal of the Japan Society of Hepatology 39 (2), 207-212, 2009-02-01

  WILEY-BLACKWELL PUBLISHING, INC

詳細情報

• CRID: 1570572700961017728
• NII論文ID: 10025324645
• NII書誌ID: AA11140867
• ISSN: 13866346
• Web Site: http://hdl.handle.net/10091/11113
• Web Site: https://soar-ir.repo.nii.ac.jp/records/3856
• Web Site: https://search.jamas.or.jp/link/ui/2009215323
• 本文言語コード: en
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