書誌事項
- タイトル別名
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- TREATMENT OUTCOME OF PATIENTS WITH PULMONARY TUBERCULOSIS BEFORE AND AFTER THE INDUCTION OF DIRECTLY OBSERVED THERAPY (DOT)
- トウイン ドクリツ ギョウセイ ホウジン コクリツ ビョウイン キコウ オオムタ ビョウイン ニ オケル インナイ DOT Directly Observed Therapy ドウニュウ ゼンゴ ノ ハイケッカク チリョウ セイセキ ノ ケントウ
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[Purpose] To evaluate the treatment outcome of patients with pulmonary tuberculosis before and after the induction of DOT.<BR>[Methods] A retrospective study of the outcome of 239tuberculosis patients treated during January 1996 to June 2003. We reviewed clinical charts collected on all patients with positive cultures for Mycobacterium tuberculosis. The patients of non-DOT group had received a traditional unsupervised drug regimen, before we have undertaken DOT. The patients of DOT group received therapy under direct observation by nurses. We compared sputum smear conversion period, sputum culture conversion period, duration of admission and treatment, recurrence rate, treatment success (cure and completion of treatment) rate and incidence of adverse effects between DOT and non-DOT group.<BR>[Results] Sp utum conversion period and incidence of adverse effects were not significantly different between both groups. The duration of admission and treatment of DOT group was significantly shorter than those of non-DOT group. Rate of relapse and treatment success was not different between two groups. Over-80-year-old patients treated by DOT revealed a higher culture conversion rate after 2-month treatment than those who were not treated with DOT.<BR>[Conclusion] We could not prove the usefu lness of DOT during hospitalization for tuberculosis patients from the points of treatment success rate and relapse rate.
収録刊行物
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- 結核
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結核 83 (10), 667-672, 2008
一般社団法人 日本結核病学会
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詳細情報 詳細情報について
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- CRID
- 1390282679978342016
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- NII論文ID
- 10025689099
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- NII書誌ID
- AN00073442
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- ISSN
- 18842410
- 00229776
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- NDL書誌ID
- 9683214
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可