毛細血管拡張症から診断したａｎｇｉｏｔｒｏｐｉｃ　Ｂ　ｃｅｌｌ　ｌｙｍｐｈｏｍａの１例

• 長阪 晶子

  山梨医科大学皮膚科

• 北嶋 敏之

  山梨医科大学皮膚科

• 山田 伸夫

  山梨医科大学皮膚科

• 島田 眞路

  山梨医科大学皮膚科

• 中村 和人

  山梨医科大学第2内科

• 柳 光章

  山梨医科大学第2内科

書誌事項

タイトル別名

• A case of Angiotropic B cell Lymphoma diagnosed by telangiectasia.

抄録

Angiotropic lymphoma is a rare lymphoproliferative disease that affects vessels of all organs especially including the skin and central nervous system. We report a 67-year-old woman with angiotropic B cell lymphoma. Examination revealed striking telangiectasia on the skin of the chest and upper back as the major manifestation. She also had subacute slight disorientation.<br>Laboratory abnormalities showed elevated serum lactic dehydrogenase (LDH) (2027U/l) . A skin biopsy from the telangiectasia revealed the presence of many intravascular, large, atypical lymphoid cells with hyperchromatic nuclei.<br>On immunohistochemical analysis, neoplastic cells showed reactivity for CD20 but not CD45RO. These findings were consistent with angiotropic B cell lymphoma. By combination chemotherapy (VAB-COP: cyclophosphamide, adriamycin, etoposide, vincristin, bleomycin and prednisolone), the telangiectasia and disorientation were dramatically improved during the follow-up period. An early diagnosis and subsequent combinatio chemotherapy may contribute to longer survival in angiotropic lymphoma. [Skin Cancer (Japan) 2002; 17: 293-295]

収録刊行物

• Ｓｋｉｎ　Ｃａｎｃｅｒ

  Ｓｋｉｎ　Ｃａｎｃｅｒ 17 (3), 293-295, 2002

  日本皮膚悪性腫瘍学会

キーワード

• Angiotropic lymphoma
• Intravascular malignant lymphomatosis
• B cell
• telangiectasia
• VAB-COP

詳細情報

• CRID: 1390282679314383872
• NII論文ID: 10025717089
• NII書誌ID: AN10087647
• DOI: 10.5227/skincancer.17.293
• ISSN: 18843549
• ISSN: 09153535
• Web Site: https://search.jamas.or.jp/link/ui/2003224015
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可