Labeling of Bifunctional Chelating Agent, MAG3, with Carrier-free 188Re

• Hashimoto Kazuyuki

  Department of Research Reactor, Japan Atomic Energy Research Institute

• Kamal W. H. B. B. Wan

  Malaysian Institute for Nuclear Technology Research

• Matsuoka Hiromitsu

  Department of Research Reactor, Japan Atomic Energy Research Institute

書誌事項

タイトル別名

• Labeling of Bifunctional Chelating Agent, MAG3, with Carrier-free <SUP>188</SUP>Re

抄録

The labeling of MAG3 with carrier-free ¹⁸⁸Re from the ¹⁸⁸W/¹⁸⁸Re generator was investigated by the direct Snreduction (solid-phase synthesis) and the indirect labeling method using citrate or gluconate as a transfer ligand. Optimum pH range were 12.1-12.6 for the direct Sn reduction, 2-5 for the use of citrate and 2.6-3 for the use of gluconate. Although the differences of the optimum conditions such as pH and reaction time at room temperature were observed by using a different transfer ligand, the labeling yield of ¹⁸⁸Re-MAG3 synthesized by the all methods was over 90% under the optimum conditions. The solid-phase synthesis requires the operation under a stream of nitrogen gas and the evaporation of solvent. On the other hand, the method using a transfer ligand is one-pot preparation by just heating a reaction mixture. Thus, judging from the ease of operations, the method using a transfer ligand is more convenient.

収録刊行物

• Ｊｏｕｒｎａｌ　ｏｆ　Ｎｕｃｌｅａｒ　ａｎｄ　Ｒａｄｉｏｃｈｅｍｉｃａｌ　Ｓｃｉｅｎｃｅｓ

  Ｊｏｕｒｎａｌ　ｏｆ　Ｎｕｃｌｅａｒ　ａｎｄ　Ｒａｄｉｏｃｈｅｍｉｃａｌ　Ｓｃｉｅｎｃｅｓ 6 (3), 193-196, 2005

  日本放射化学会

詳細情報

• CRID: 1390282679457521280
• NII論文ID: 10025719449
• NII書誌ID: AA11948402
• DOI: 10.14494/jnrs2000.6.3_193
• COI: 1:CAS:528:DC%2BD28XjtFSju7s%3D
• ISSN: 18835813
• ISSN: 13454749
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可