ゼラチンとスクロースを用いた拡散強調画像用ファントムの検討 田村 隆行 笛吹 修治 秋山 實利 公益社団法人 日本放射線技術学会 日本放射線技術學會雜誌 03694305 65 11 1485 1493 2009-11-20 When studying diffusion weighted imaging(DWI), it is important to create a phantom that has a reliably controlled diffusion coefficient. In this study, we investigated phantoms to control both the diffusion coefficient and the T2-value by changing the concentration of gelatin or sucrose and MnCl2, respectively. The results showed that the diffusion coefficient decreased linearly with increases in the gelatin or sucrose concentration, and decreasing of their relaxation times was observed. By properly adjusting the MnCl2 concentrations, we were able to equalize the T2-values between phantoms having different gelatin or sucrose concentrations. Temperature dependence of the diffusion coefficient was also revealed. This phantom can be made stable for a few months by adding a small amount of NaN3 as an antiseptic agent, has a diffusion coefficient similar to that of neural tissue or clinical tumor, and is able to control the T2-value properly. We consider this phantom suitable for studying SE-type DWI and contributes to elucidation of this technique. 2009-11-20 10025977746 AN00197784 10506985 JPN CJP NDL J-STAGE 0 14 Investigation of a Phantom for Diffusion Weighted Imaging That Controlled the Apparent Diffusion Coefficient Using Gelatin and Sucrose TAMURA Takayuki USUI Shuji AKIYAMA Mitoshi Japanese Society of Radiological Technology Japanese Journal of Radiological Technology When studying diffusion weighted imaging(DWI), it is important to create a phantom that has a reliably controlled diffusion coefficient. In this study, we investigated phantoms to control both the diffusion coefficient and the T2-value by changing the concentration of gelatin or sucrose and MnCl2, respectively. The results showed that the diffusion coefficient decreased linearly with increases in the gelatin or sucrose concentration, and decreasing of their relaxation times was observed. By properly adjusting the MnCl2 concentrations, we were able to equalize the T2-values between phantoms having different gelatin or sucrose concentrations. Temperature dependence of the diffusion coefficient was also revealed. This phantom can be made stable for a few months by adding a small amount of NaN3 as an antiseptic agent, has a diffusion coefficient similar to that of neural tissue or clinical tumor, and is able to control the T2-value properly. We consider this phantom suitable for studying SE-type DWI and contributes to elucidation of this technique. 田村 隆行 TAMURA Takayuki 広島原爆障害対策協議会健康管理増進センター放射線科 Department of Radiology, Hiroshima Atomic Bomb Casualty Council, Health Management & Promotion Center 笛吹 修治 USUI Shuji 広島国際大学保健医療学部診療放射線学科 Department of Clinical Radiology, Faculty of Health Science, Hiroshima International University 秋山 實利 AKIYAMA Mitoshi 広島国際大学保健医療学部診療放射線学科 Department of Clinical Radiology, Faculty of Health Science, Hiroshima International University