Spacing of the Embryo in the Uterus is Disrupted by the Supine Position of the Body During the Peri-implantation Period in Mice
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- SUGIYAMA Makoto
- Laboratory of Basic Veterinary Science, United Graduate School of Veterinary Science, Yamaguchi University
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- TERAKAWA Jumpei
- Laboratory of Basic Veterinary Science, United Graduate School of Veterinary Science, Yamaguchi University
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- KHAN Hamayun
- Laboratory of Basic Veterinary Science, United Graduate School of Veterinary Science, Yamaguchi University
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- WAKITANI Shoichi
- Laboratory of Basic Veterinary Science, United Graduate School of Veterinary Science, Yamaguchi University
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- CHOI Ehn-Kyoung
- Laboratory of Basic Veterinary Science, United Graduate School of Veterinary Science, Yamaguchi University
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- KISO Yasuo
- Laboratory of Basic Veterinary Science, United Graduate School of Veterinary Science, Yamaguchi University
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- HONDO Eiichi
- Laboratory of Basic Veterinary Science, United Graduate School of Veterinary Science, Yamaguchi University
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抄録
This study aimed to clarify the mechanism of the spacing of murine embryos along the metrial and anti-metrial (MA) axis of the uterus using our newly developed experimental model. The model mice were produced by keeping mice in the supine position from the pre-implantation to implantation period. The starting points and periods of restraint of the mice in the supine position were set variously during the peri-implantation. Then, the position of the embryo was evaluated morphologically. In only one group (set in the instrument from the second day of pregnancy, Day 2, to Day 5), strong disruption of embryo spacing along the MA axis was observed. On the other hand, there was little abnormality in embryo positioning in the groups that were treated from Day 3 to Day 5 or from Day 3 to Day 6. These results suggested that determination of the position of the embryo in the MA axis is not related to duration of the experiment (2 days or 3 days), but is related to the starting time-point of the experiment, at Day 2 or Day 3. In conclusion, the period between Days 2 and 3 is critical for determination of the position of the embryo along the MA axis. <br>
収録刊行物
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- Journal of Reproduction and Development
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Journal of Reproduction and Development 56 (2), 191-194, 2010
公益社団法人 日本繁殖生物学会
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詳細情報 詳細情報について
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- CRID
- 1390001206336935680
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- NII論文ID
- 10026324210
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- NII書誌ID
- AA10936678
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- ISSN
- 13484400
- 09168818
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- NDL書誌ID
- 10656402
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可