A National Survey on Myocarditis Associated With the 2009 Influenza A (H1N1) Pandemic in Japan

• Ukimura Akira

  Department of General Internal Medicine, Osaka Medical College

• Izumi Tohru

  Department of Internal Medicine, Kitasato University School of Medicine

• Matsumori Akira

  Department of Cardiology, Tokyo Medical University

• Clinical Research Committee on Myocarditis Associated with the 2009 Influenza A (H1N1) Pandemic in Japan organized by the Japanese Circulation Society

• Nakamura Makiko

• Nishioka Kenji

• Kanai Eri

• Jibiki Toshiaki

• Shikama Nobuaki

• Imaki Ryuta

• Iwata Tomohiko

• Sone Takahito

• Takeshima Hiroshi

• Tanabe Yasuhiro

• Endo Tomoyuki

• Amano Tomonori

• Takama Noriaki

抄録

Background: An influenza pandemic occurred in 2009 and myocarditis associated with the 2009 influenza A (H1N1) pandemic was reported among hospitalized patients from August 2009. Methods and Results: The Japanese Circulation Society organized the Clinical Research Committee on Myocarditis Associated with Influenza Pandemic A (H1N1) 2009 and called for a case report on myocarditis for a national survey. The diagnosis of myocarditis was performed using the Guidelines for the Diagnosis and Treatment of Myocarditis (JCS 2009). Fifteen patients were reported to the committee. Fulminant myocarditis developed in 10 patients. Mechanical circulatory support (intra-aortic balloon pumping (IABP) and/or percutaneous cardiopulmonary support (PCPS)) was used on all 10 patients, 8 of whom were rescued. Abnormalities on echocardiography and elevated cardiac enzymes were seen in most of the patients. Myocarditis was found by endomyocardial biopsy in 6 patients. Three patients had complications with pneumonia. Conclusions: In reality, myocarditis associated with pandemic influenza A (H1N1) seemed to be more common in hospitalized patients, compared with previous seasonal influenza virus outbreaks. To avoid misdiagnosis of acute myocarditis associated with influenza pandemic A (H1N1) 2009, it is essential to determine the characteristic symptoms, signs, and laboratory findings of acute myocarditis during influenza pandemics. Mechanical circulatory support (IABP and/or PCPS) was required to rescue patients with fulminant myocarditis. (Circ J 2010; 74: 2193-2199)<br>

収録刊行物

• Circulation Journal

  Circulation Journal 74 (10), 2193-2199, 2010

  一般社団法人 日本循環器学会

キーワード

• Influenza
• Myocarditis
• Pandemic

詳細情報

• CRID: 1390001205101763584
• NII論文ID: 10026640631
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.cj-10-0452
• COI: 1:STN:280:DC%2BC3cflvFKisw%3D%3D
• ISSN: 13474820
• ISSN: 13469843
• PubMed: 20697177
• Web Site: https://search.jamas.or.jp/link/ui/2011066642
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • PubMed
  • CiNii Articles
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