長期にわたり聴力経過観察をした前庭水管拡大症の２症例

• 石橋 康子

  三井記念病院耳鼻咽喉科

• 山岨 達也

  東京大学医学部耳鼻咽喉科学教室

• 宇佐美 真一

  信州大学医学部耳鼻咽喉科学教室

• 阿部 聡子

  弘前大学医学部耳鼻咽喉科学教室

• 加我 君孝

  東京大学医学部耳鼻咽喉科学教室

書誌事項

タイトル別名

• Long term observation of two cases of large vestibular aqueduct syndrome.

抄録

Two cases of large vestibular acqueduct syndrome (LVAS) are presented.<BR>The first case was a 13-year-old boy, who had been observed 9 years. At the initial examination, hearing threshold was 80dB in the left ear and 60dB in the right ear. He experienced acute hearing deterioration four times, at each time hearing showed recovery by oral administration of steroids, vitamin B12. He was found to have a mutation in the chromosome 7q31.<BR>The second case was a 21-year-old women and she had been observed for 14 years. Initially a pure-tone audiogram showed 65dB hearing loss bilaterally. She had experienced acute hearing deterioration accompanied or unaccompanied by vestibular disturbance 11 times.<BR>Steroid hormone and vitamin B12 given at each episode were effective. Hearing thresholds at the last pure tone audiogram were 70dB of the left, and 80dB on the right. These findings suggested that hearing deterioration the LVAS could be managed for long term by conservative treatment.

収録刊行物

• Ｏｔｏｌｏｇｙ　Ｊａｐａｎ

  Ｏｔｏｌｏｇｙ　Ｊａｐａｎ 13 (1), 57-61, 2003

  一般社団法人　日本耳科学会

キーワード

• large vestibular aqueduct syndrome
• SLC26A4 (<I>PDS</I>)
• gene

詳細情報

• CRID: 1390001204768901760
• NII論文ID: 10026920363
• NII書誌ID: AN10358085
• DOI: 10.11289/otoljpn1991.13.57
• ISSN: 18841457
• ISSN: 09172025
• Web Site: https://search.jamas.or.jp/link/ui/2003185975
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可