１０年後皮膚転移を認めた平滑筋肉腫の１例

DOI 機関リポジトリ 被引用文献1件 参考文献6件

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  • Leiomyosarcoma with delayed cutaneous metastases after 10 years disease-free interval

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A 73-year-old man with cutaneous metastases from leiomyosarcoma is reported. The primary lesion on the upper back had been excised 13 years ago in 1988. In March 1991 local recurrence was noted and he received wide resection followed by CYVADIC chemotherapy and 50Gy irradiation. In March 2002 he noticed an asymptomatic 3.5 cm-sized nodule on his left elbow. Histologically, the tumor was composed of spindle cells with blunted nuclei in fascicular pattern. Immunohistological analysis showed that the tumor cells were positive for vimentin and α-smooth muscle actin. Following wide resection of the metastatic skin lesion, no recurrence or distant metastases were noted after 22 months' follow-up. [Skin Cancer (Japan) 2005; 20: 62-65]

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