Aspartame-Acesulfame K-containing Low-Energy Erythritol Sweetener Markedly Suppresses Postprandial Hyperglycemia in Mild and Borderline Diabetics

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In diabetic patients, compliance to diet therapy has been an ongoing concern. We thus examined the effects of an aspartame-and acesulfame K-containing sweetener (PZ) on postprandial hyperglycemia in mild and borderline diabetics. In two sets of crossover, randomized, placebo-controlled, double-blind tests, subjects with mild or borderline diabetes were challenged with meals consisting of white rice, and two side dishes flavored with PZ (PZ meal) or sugar (Control meal); or with sweets flavored with PZ (PZ sweets) or sugar (Control sweets). The use of PZ (PZ meal and PZ sweets) significantly reduced postprandial levels, particularly at 1 h, of blood glucose and insulin when compared to sugar (Control meal and Control sweets). The results demonstrated that PZ as a sugar substitute enabled the suppression of postprandial hyperglycemia in mild or borderline diabetics without compromising palatability, sweetness or patient QOL.

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詳細情報

  • CRID
    1390001204459838848
  • NII論文ID
    10027497504
  • NII書誌ID
    AA11320122
  • DOI
    10.3136/fstr.16.457
  • ISSN
    18813984
    13446606
  • 本文言語コード
    en
  • データソース種別
    • JaLC
    • Crossref
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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