Antioxidative Pyranonigrins in Rice Mold Starters and Their Suppressive Effect on the Expression of Blood Adhesion Molecules

DOI Web Site Web Site 被引用文献10件 参考文献34件
  • MIYAKE Yoshiaki
    Faculty of Human Wellness, Tokaigakuen University
  • MOCHIZUKI Mika
    Faculty of Human Wellness, Tokaigakuen University Laboratory of Food and Biodynamics, Graduate School of Bioagricultural Sciences, Nagoya University
  • ITO Chihiro
    Faculty of Pharmacy, Meijo University
  • ITOIGAWA Masataka
    Faculty of Human Wellness, Tokaigakuen University
  • OSAWA Toshihiko
    Laboratory of Food and Biodynamics, Graduate School of Bioagricultural Sciences, Nagoya University

この論文をさがす

抄録

Antioxidants having a 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging capacity in rice mold starters, which are used for the preparation of various Japanese fermented foods, and their effectiveness against the expression of blood adhesion molecules were examined. An antioxidant was isolated from the rice mold starters used for shochu and identified as pyranonigrin-S (PG-S) by 1H-NMR, 13C-NMR, and FAB-MS analyses. It was a derivative of pyranonigrin-A (PG-A), which has been isolated as an antioxidant from the rice mold starters. Pyranonigrins PG-A and PG-S were found to exist in spores on rice mold starters which had been prepared by Aspergillus awamori, A. kawachii, and A. saitoi. PG-S exhibited a higher level of DPPH radical scavenging activity than PG-A. PG-A was found to have a significant suppressive effect on the expression of vascular cell adhesion molecule-1 (VCAM-1) in human umbilical vein endothelial cells (HUVECs) induced by tumor necrosis factor-α (TNF-α) (P<0.05).

収録刊行物

被引用文献 (10)*注記

もっと見る

参考文献 (34)*注記

もっと見る

関連プロジェクト

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ